Researchers discover what happens when a heart-shaped vessel forms inside a heart muscle
Scientists at the University of Melbourne and Wageningen University have found that the growth of a vessel inside the heart increases the likelihood of an inflammatory reaction.
The findings could lead to a better understanding of heart disease and heart failure, they said.
Heart Vessels: An Insights into Their Structure and Function article The heart-like structures inside our hearts can function as vessels, which help our bodies fight infection and heal wounds.
However, these structures are very fragile and the formation of a large vessel inside a human heart has been associated with a number of conditions including heart failure.
Heart-shaped structures are found inside the walls of our arteries, known as the coronary arteries, and the vessel within the heart can become damaged and block blood flow.
The vessel within a heart is called the aneurysm and is a very important organ for our health.
The most common causes of heart failure are heart attacks, and although the process of forming a large aneurysis is not well understood, the process has been linked to the progression of atherosclerosis, a type of plaque that accumulates in the heart.
“We found that in some people, the formation and growth of an aortic vessel is associated with increased risk of cardiovascular disease, including heart attacks,” Dr Andrew Williams, one of the study’s authors, told New Scientist.
“Our results provide new insight into how a large heart-sized vessel develops inside a person’s heart and suggest that we may need to better understand the mechanism underlying this process.”
The team used an imaging technique called magnetic resonance imaging to look at the structure of the anaerobic stromal cells inside the vessel inside of the heart, and they found that they grow at a rate of up to two per cent per day.
The researchers believe that the increased growth of the cells is related to a more efficient way of carrying out chemical reactions that produce energy and oxygen.
In addition, the growth in the antero-ventricular (AV) chamber may lead to the formation more efficient valves in the vessel that help it expand.
A large vessel has a much higher capacity to carry out these chemical reactions than a small one, so these vessels are able to carry more oxygen, which in turn helps the vessel to heal.
It is unknown how the anthers in the vessels are formed, and whether the increased oxygen helps the cells to grow or whether the vessel itself is the cause of the increased cell growth.
“Although this is a relatively new and exciting study, it also highlights the need to understand the molecular mechanisms behind how this process occurs,” Dr Williams said.
“This will enable us to develop better treatments for heart failure and other conditions that can occur as a result of abnormal growth of heart-related cells.”
The findings are published in the journal Nature Communications.
The study was funded by the Australian Research Council (ARC), the Australian Medical Research Council, the Medical Research Future Fund, and ARC’s Health Research Future Fellowship.
The team also received support from the European Union.
About The Australian Heart Foundation The Australian heart foundation supports the research of Australia’s leading cardiac surgeons, nurses, academics and researchers, and provides high-quality medical education, clinical research and training for our nation’s health professionals.
The foundation was established in 2004 to fund clinical research into the causes and treatments of heart diseases and other cardiovascular problems.